Protein Details: Two-pore potassium channel 5

Protein ID

ICDB_Pro_1624

Protein Name

Two-pore potassium channel 5

Gene Name

TPK5; KCO5; At4g01840; T7B11.10

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

408 amino acids

AlphaFoldDB

AF-Q9S6Z8-F1-model_v4.pdb

Function

Probable voltage-independent potassium-selective tonoplast ion channel

Sequence

MEPLISPQPRFRLQPIPENPSSSSSSASITIPRSISNTSFFHEISQERLLLHHQDLEQSVQDDKEDQDSDSDETNRFLSQTRPLHRSRTAPAMVIIKDLRTKPPETKKPSPVSKSIIRQAIFLLIVYLTLGVSIYSFNRDHYSGIETHPVVDALYFCIVTMCTIGYGDIAPLTPWTKIFAVVFVLFGFGFLDILLSGVVNYVLDLQESMILTGIQTRQHHQHHHHHRFSAKDYIIDFEKGRMRIRMKVCLALCVVVLCIGVGALVLHFVEELGFVDSVYLSVMSVTTVGYGDRAFKTLQGRLFAAVWLLVSTLAVARAFLYLAEARIDRRHRKAVKLALNREITVDDLLKADTYQHGFISKSEYIVLKLKEMGKITQKDIDQVVIQFEKLDPNQIGKITLPDLLGDPL

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

352;363;391;393;397;402

Disease

Location

Expressed in hydathodes and the vascular tissues of roots; stems; leaves and flowers.

DOI ID

10.1111/tpj.13415; 10.1104/pp.126.4.1646; 10.1073/pnas.0401502101; 10.1111/j.1365-313x.2007.03255.x

RefSeq

NP_192093.1